Top Grade Low Price Pure Hydrolyzed collagen powder, Digestibility Hydrolyzed collagen, CAS 9064-67-9

 Hydrolyzed collagen is produced from collagen found in the bones, skin, and connective tissue of animals such as cattle, fish, horses, pigs, and rabbits. The process of hydrolysis involves breaking down the molecular bonds between individual collagen strands using combinations of heat, acids, alkalis, or enzymes. Typically, with skin-sourced collagen, hides are put in a lime slurry pit for up to 3 months, loosening collagen bonds; the hides are then washed to remove lime, and the collagen extracted in boiling water. The extracted collagen is evaporator concentrated, desiccated with drum driers, and pulverized.

Amino acid content

Hydrolyzed collagen contains 8 out of 9 essential amino-acids,  including glycine and arginine —two amino-acid precursors necessary for thebiosynthesis of creatine. It contains no tryptophan and is deficient in isoleucine, threonine, and methionine.

Digestibility

The bioavailability of hydrolyzed collagen in mice was demonstrated in a 1999 study; orally administered 14C hydrolyzed collagen was digested and more than 90% absorbed within 6 hours, with measurable accumulation in cartilage and skin.  A 2005 study in humans found hydrolyzed collagen absorbed as small peptides in the blood.

Effects on skin

Ingestion of hydrolyzed collagen may affect the skin by increasing the density of collagen fibrils and fibroblasts, thereby stimulating collagen production.  It has been suggested, based on mouse and in vitro studies, that hydrolyzed collagen peptides have chemotactic properties on fibroblasts or an influence on growth of fibroblasts.

Joint and bone effects

Some clinical studies report that the oral ingestion of hydrolyzed collagen decreases joint pain, those with the most severe symptoms showing the most benefit.   Beneficial action is likely due to hydrolyzed collagen accumulation in the cartilage  and stimulated production ofcollagen by the chondrocytes, the cells of cartilage.  Several studies have shown that a daily intake of hydrolyzed collagen increases bone mass density.  It seems that hydrolyzed collagen peptides stimulated differentiation and osteoblasts activity- the cells that build bone- over that of osteoclasts (cells that destroy bone).

However, other clinical trials have yielded mixed results. In 2011, the European Food Safety Authority Panel on Dietetic Products, Nutrition and Allergies concluded that "a cause and effect relationship has not been established between the consumption of collagen hydrolysate and maintenance of joints".  Four other studies reported benefit with no side effects; however, the studies were not extensive, and all recommended further controlled study.  One study found that oral collagen only improved symptoms in a minority of patients and reportednausea as a side effect.  Another study reported no improvement in disease activity in patients with rheumatoid arthritis.   Another study found that collagen treatment may actually cause an exacerbation of rheumatoid arthritis symptoms.

Cosmetics

In cosmetics, hydrolyzed collagen may be found in topical creams, acting as a product texture conditioner, and moisturizer.

Performance:

With a very strong bioactivity and biological function, fish skin collagen is a kind of natural protein which is able to participate in the migration, differentiation and reproduction of cells and provide the bone tendon, cartilage and skin with a certain mechanical strength. Due to its weak antigenicity and its good biological compatibility, the collagen is widely used in medical care fields, such as burning, injury or wound, cornea diseases, make-ups, firm tissue repair, wound surface hemostasia and so on. Our company selected the fish skin from the Tilapia mossambic as the raw materials for the collagen which is produced by the application of modern biological enzymolysis technology. Rich with different varieties of amino acids, the product is very easy to be digested and absorbed with its molecular weight ranging from 1000 to 5000D in length. It also has a wonderful thermo-stability in the water. The collagen of this variety has admirable compatibility with the skin of human beings, able to penetrate, rehabilitate and recover the skin and keep its humidity.
 

1. Make-up and skin-caring: The natural moisture-keeping factors contained in this product have the functions on humidity-keeping, wrinkle preventing and nutrition supplying to human bodies, able to make the skin more delicate, lustrous and flexible. Therefore, this product is a sort of high quality material for face, also a high quality raw material for advanced moisturizing cream and cleansing milk. Meanwhile, it can be used in shampoo, hair care cream, and bath foam.
2. Medical care product: With the functions of adjusting metabolism, discharging the waste in human bodies, invigorating the spleen and preventing senescence, it is particularly suitable for the growth of children and nutrition Supplement for middle aged and elderly people. Therefore, it is popular as a drug and health caring product.
3. Food: The product can be added to bread, cakes and different varieties of refreshments to improve their nutrition structure. Nutritious jelly produced by its liquid product is extremely effective to children and valetudinarianism as well those weak in dyspepsia. It can also be added to beverage as protein supplement to make the bodies stronger.

Suggestion on its application: 

It is suggested that an amount of 1-5% of this product be added to make-ups while 1-10% to food.